Sevelamer hydrochloride
- Product Name
- Sevelamer hydrochloride
- CAS No.
- 152751-57-0
- Chemical Name
- Sevelamer hydrochloride
- Synonyms
- Sevelemar;SEVELAMER HCL;Sevelamer-001;Tianeptinic acid;SevelaMer HCL API;Sevelamer Hydrochloride;Sevelamer Hydrochloride (100 mg);Sevelamer hydrochloride USP/EP/BP;Sevelamer hydrochloride Impurities;TIANFU-CHEM Sevelamer hydrochloride
- CBNumber
- CB91012045
- Molecular Formula
- C6H13Cl2NO
- Formula Weight
- 186.08
- MOL File
- 152751-57-0.mol
Sevelamer hydrochloride Property
- storage temp.
- Store at -20°C
- solubility
- Hot Methanol (Sparingly)
- form
- Solid
- color
- Pale Yellow
N-Bromosuccinimide Price
- Product number
- S256000
- Product name
- SevelamerHydrochloride(TechnicalGrade)
- Packaging
- 500mg
- Price
- $225
- Updated
- 2021/12/16
- Product number
- E121
- Product name
- Sevelamerhydrochloride
- Packaging
- 500mg
- Price
- $225
- Updated
- 2021/12/16
- Product number
- CS-3149
- Product name
- Sevelamerhydrochloride
- Purity
- >98.0%
- Packaging
- 500mg
- Price
- $324
- Updated
- 2021/12/16
- Product number
- CS-3149
- Product name
- Sevelamerhydrochloride
- Purity
- >98.0%
- Packaging
- 100mg
- Price
- $90
- Updated
- 2021/12/16
Sevelamer hydrochloride Chemical Properties,Usage,Production
Originator
Renagel,Chugai Pharmaceutical
Uses
Sevelamer HCl is used in the treatment of hyperphosphataemia in patients suffering from chronic kidney disease.
Uses
Sevelamer hydrochloride is a noncalcemic phosphate binder for the treatment of hyperphosphatemia in chronic renal failure or patients suffering from chronic kidney disease.
Definition
ChEBI: Sevelamer hydrochloride is an epoxide.
Manufacturing Process
Poly(allylamine hydrochloride) (50% w/w, 426 kg) was charged to a 1000 L reactor and water (200 L) was added. Sodium hydroxide solution (32% w/w,
208 kg) was added, followed by 85 L of water. The mixture was stirred for 1 h
and filtered to a 2500 L reactor. The transfer line was rinsed with water (217
kg) and acetonitrile (1300 L) added. The temperature was adjusted to 40°C
and epichlorohydrin (20 kg) added. The mixture was stirred at 40° to 50°C for
1.5 h and then heated to reflux for 16 h. The resulting product slurry may be
isolated and washed in decanter centrifuge.
brand name
Renagel (Genzyme).
Therapeutic Function
Antihyperphosphatemic
Veterinary Drugs and Treatments
Sevalamer may be useful for treating hyperphosphatemia associated with chronic renal failure, particularly when oral aluminum salts are not tolerated.
Sevelamer hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Sevelamer hydrochloride Suppliers
View Lastest Price from Sevelamer hydrochloride manufacturers
- Product
- Sevelamer hydrochloride 152751-57-0
- Price
- US $9.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 50000tons
- Release date
- 2023-07-31
- Product
- Sevelamer hydrochloride 152751-57-0
- Price
- US $5.00/kg
- Min. Order
- 1kg
- Purity
- >99%
- Supply Ability
- 300000ton
- Release date
- 2023-03-14
- Product
- Sevelamer hydrochloride 152751-57-0
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.9%
- Supply Ability
- 100 Tons min
- Release date
- 2021-08-04